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How to sex mice

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The female presence in labs is completely under-represented, and I'm not talking about humans here, but mice. The most used animal model in laboratories across the world to discover and test new medicines are almost entirely male. And it is time to fight for equal female health rights in the lab too. The reason is that over-reliance on male mice in the medicine development process can leave women taking drugs at an inappropriate dose and even suffering side-effects that men rarely feel.
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Male mice hard-wired to recognize sex of other mice

How to sex mice
How to sex mice
How to sex mice
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Male mice hard-wired to recognize sex of other mice -- ScienceDaily

Researchers at the Chinese Academy of Sciences have produced healthy mice with two mothers, who were then able to go on to reproduce themselves. Using female same-sex parents, the scientists were able to produce a total of 29 live mice from embryos. All these offspring were normal, lived to adulthood, and were able to give birth to offspring of their own. The study, published in scientific journal Cell Stem Cell , examined why same-sex mammals are not typically able to reproduce, suggesting stem cells and targeted gene editing can make the process easier. He said in mammals, certain maternal or paternal genes are shut off during the development of sperm and egg cells, meaning offspring that do not receive genetic material from both a mother and father might experience developmental abnormalities. By deleting imprinted genes from immature eggs, researchers have in the past been able to produce mice with two mothers, although most still displayed genetic defects. Alongside the 29 healthy mice produced by same-sex female parents, a dozen mice were also born to two male parents during the course of the study.
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Pheromone in baby mouse tears makes females less interested in sex

All rights reserved. Thanks to gene editing, two mouse moms birthed this pup. Now grown to adulthood, she even has her own babies. Birds do it, bees do it—even laboratory mice do it. But with science in the mix, actually creating new life may not always require a male and a female.
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